A SODIUM SALT OF N-((1,2,3,5,6,7-HEXAHYDRO-S-INDACEN-4 -YL)CARBAMOYL)-1-ISOPROPYL-1H-PYRAZOLE-3-SULFONAMIDE

The present invention relates to a sodium salt ofN-((1,2,3,5,6,7-hexahydro-s-indacen-4-yl)carbamoyl)-1-isopropyl-1H-pyrazole-3-sulfonamide and to hydrates, solvates and polymorphic forms thereof. The present invention further relates to pharmaceutical compositions comprising this compound and the us...

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Bibliographic Details
Main Authors STRATFORD, SAMUEL, ALEXANDER, MILLER, DAVID, DEL RIO, GANCEDO, SUSANA, MACLEOD, ANGUS
Format Patent
LanguageEnglish
Serbian
Published 30.09.2020
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to a sodium salt ofN-((1,2,3,5,6,7-hexahydro-s-indacen-4-yl)carbamoyl)-1-isopropyl-1H-pyrazole-3-sulfonamide and to hydrates, solvates and polymorphic forms thereof. The present invention further relates to pharmaceutical compositions comprising this compound and the use of this compound in the treatment and prevention of medical disorders and diseases, most especially by NLRP3 inhibition.
Bibliography:Application Number: RS2020P000936