SYK INHIBITORS
The present disclosure relates to compounds that are Syk inhibitors and to their use in the treatment of various disease states, including cancer and inflammatory conditions. In particular embodiments, the structure of the compounds is given by Formula I: wherein R 1 , R 2 , R 3 , and R 4 are as des...
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| Main Authors | , , , , , , , , , , |
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| Format | Patent |
| Language | English Serbian |
| Published |
31.07.2018
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| Subjects | |
| Online Access | Get full text |
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| Abstract | The present disclosure relates to compounds that are Syk inhibitors and to their use in the treatment of various disease states, including cancer and inflammatory conditions. In particular embodiments, the structure of the compounds is given by Formula I: wherein R 1 , R 2 , R 3 , and R 4 are as described herein. The present disclosure further provides pharmaceutical compositions that include a compound of Formula I, or pharmaceutically acceptable salts or co-crystals thereof, and methods of using these compounds and compositions to treat conditions mediated by Syk. |
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| AbstractList | The present disclosure relates to compounds that are Syk inhibitors and to their use in the treatment of various disease states, including cancer and inflammatory conditions. In particular embodiments, the structure of the compounds is given by Formula I: wherein R 1 , R 2 , R 3 , and R 4 are as described herein. The present disclosure further provides pharmaceutical compositions that include a compound of Formula I, or pharmaceutically acceptable salts or co-crystals thereof, and methods of using these compounds and compositions to treat conditions mediated by Syk. |
| Author | SCHMITT, AARON, C KROPF, JEFFREY, E CURRIE, KEVIN, S ZHAO, ZHONGDONG LO, JENNIFER, R XIONG, JIN-MING XU, JIANJUN SWAMINATHAN, SUNDARAMOORTHI LEE, SEUNG, H BLOMGREN, PETER, A MITCHELL, SCOTT, A |
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| Notes | Application Number: RS2018P000332 |
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| Snippet | The present disclosure relates to compounds that are Syk inhibitors and to their use in the treatment of various disease states, including cancer and... |
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| Title | SYK INHIBITORS |
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