FERROMAGNETIC SHAPE-MEMORY BIOMATERIALS COATED WITH BIOCOMPATIBLE POLYMERS

• Main Authors: TUDORAN CRISTIAN, TURCU RODICA PAULA, TOLEA FELICIA, NAN ALEXANDRINA EMILIA, POEATA ION, SOFRONIE MIHAELA, CHIRIAC ALEXANDRU
• Format: Patent
• Language: English; Romanian
• Published: 30.06.2022
• Subjects: AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F,C08G; BANDAGES, DRESSINGS OR ABSORBENT PADS; CHEMISTRY; COMPOSITIONS BASED THEREON; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF,TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; FILTERS IMPLANTABLE INTO BLOOD VESSELS; FIRST-AID KITS; FOMENTATION; GENERAL PROCESSES OF COMPOUNDING; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC MACROMOLECULAR COMPOUNDS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; PROSTHESES; THEIR PREPARATION OR CHEMICAL WORKING-UP; TREATMENT OR PROTECTION OF EYES OR EARS; WORKING-UP

The invention relates to a process for making ferromagnetic shape memory biomaterials coated with biocompatible polymers, applicable in personalized implantology medical devices. According to the invention, the process consists of the following stages: activation of the metallic surface in cold plasma, at the atmospheric pressure, on both faces of the FePd-based ferromagnetic strips, both non-doped and doped with different metallic ions, such as manganese and gallium, pulverization thereon of a methanol solution in which polymers, such as poly (benzofurane-co-arylacetic acid) (PBAAA) and polyglutamic acid (PGA), have been dissolved, drying of the strips at the room temperature for 24 h and washing in a distillation water bath, to result in functionalized hemocompatible biomaterials. Invenţia se referă la un procedeu de obţinere a unor biomateriale feromagnetice cu memoria formei acoperite cu polimeri biocompatibili cu aplicabilitate ca dispozitive medicale implantologice personalizate. Procedeul, conform invenţiei, constă în etapele: activarea suprafeţei metalice în plasmă rece la presiune atmosferică, pe ambele părţi ale benzilor feromagnetice pe bază de FePd nedopate, respectiv, dopate cu ioni metalici diferiţi de tip mangan şi galiu, aplicarea prin pulverizare a unei soluţii de metanol în care sunt dizolvaţi polimerii de tip poli(benzofuran-co-acid arilacetic) (PBAAA) şi acid poliglutamic (PGA), uscarea benzilor la temperatura camerei timp de 24 h şi spălare într-o baie de apă distilare, rezultând biomateriale funcţionalizate hemocompatibile.