PROCESS FOR COATING SURGICAL INSTRUMENT USEFUL SURFACES WITH AU AND AG NANOSTRUCTURES AND SURGICAL INSTRUMENT OBTAINED THEREBY FOR INTRASURGICAL ASSESSMENT OF TUMOUR MARGIN STATUS

• Main Authors: MANEA SORIN, GRIGORESCU CRISTIANA EUGENIA ANA, RUSU MĂDĂLIN ION, SCOICARU LAURENŢIU OCTAVIAN, MILITARU MANUELLA, UDREA VIRGIL MIRCEA, BÎRŢOIU ION ALIN, CHIRICUTA BOGDAN, MUNTEANU RALUCA MĂDĂLINA, VIŢĂLARU BOGDAN ALEXANDRU
• Format: Patent
• Language: English; Romanian
• Published: 29.11.2022
• Subjects: CHEMICAL SURFACE TREATMENT; CHEMISTRY; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATIONOR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY IONIMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL; COATING MATERIAL WITH METALLIC MATERIAL; COATING METALLIC MATERIAL; DIAGNOSIS; DIFFUSION TREATMENT OF METALLIC MATERIAL; HUMAN NECESSITIES; HYGIENE; IDENTIFICATION; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION INGENERAL; MEDICAL OR VETERINARY SCIENCE; METALLURGY; SURFACE TREATMENT OF METALLIC MATERIAL BY DIFFUSION INTO THESURFACE, BY CHEMICAL CONVERSION OR SUBSTITUTION; SURGERY

The invention relates to a process for coating the useful surfaces of a surgical instrument intended for intrasurgical assessment of surgical margins of tumours and determining the type thereof. According to the invention, the process consists in preparing, in an essential oil for medical use, a solution of metallic nanopowders of Au having the size of 10...30 nm and Ag, respectively, having a purity of 99.9%, in a concentration of 20...50%, at the ambient temperature, after which it is deposited in an amount of 0.01...0.05 ml onto the useful steel surfaces of the instrument, by centrifugation, at a rotary speed of 500...1000 rpm, the resulting film being dried for 120...180 min at the ambient temperature, heat treated in a vacuum oven of 10Torr, at 150...190°C, for 70...100 min, with natural cooling down to the ambient temperature, resulting in a nano structured coating of Au and Ag of uniform roughness, which adheres to the useful surfaces, is resistant to the usual sterilization temperature, oxidation- and exfoliation-proof.