TAXOL DERIVATIVE AND PROCESS FOR PREPARING THE SAME

The invention relates to a taxol derivative and namely, 4, 10-diacetoxy-2 alpha- benzoyloxy -5 beta, 20-epoxy - 1,7 beta - dihydroxy- 9 - oxo - tax - 11 - en - 13 alpha - yl, (2R, 3S) - 3 - benzoylamino - 2 - hydroxy - 3 - phenylpropionate trihydrate, and it also relates to a process for preparing t...

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Bibliographic Details
Main Authors DIDIER ERIC, LEVEILLER FRANCK, AUTHELIN JEAN RENE, TAILLEPIED ISABELLE
Format Patent
LanguageEnglish
Romanian
Published 30.05.2000
Edition7
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The invention relates to a taxol derivative and namely, 4, 10-diacetoxy-2 alpha- benzoyloxy -5 beta, 20-epoxy - 1,7 beta - dihydroxy- 9 - oxo - tax - 11 - en - 13 alpha - yl, (2R, 3S) - 3 - benzoylamino - 2 - hydroxy - 3 - phenylpropionate trihydrate, and it also relates to a process for preparing the same by crystallization from a water/alcohol solution, said product having outstanding anticancer and antileukemic characteristics
Bibliography:Application Number: RO19970001401