PROCESS FOR PREPARING ENANTIOMERICALLY PURE 6-/(4-CHLOROPHENYL)(1H-1, 2, 4 - TRIAZOLE-1-YL) METHYL/-1-METHYL-1H-BENZOTRIAZOLE AND INTERMEDIATE FOR PREPARING THE SAME

PCT No. PCT/EP93/03066 Sec. 371 Date Apr. 18, 1995 Sec. 102(e) Date Apr. 18, 1995 PCT Filed Nov. 2, 1993 PCT Pub. No. WO94/11364 PCT Pub. Date May 26, 1994A process for preparing (+)-6-[(4-chlorophenyl)(1H-1,2,4-triazol-1-yl)methyl]-1-methyl-1H-benzotriazole comprising the resolution of (+/-)-6-[(4-...

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Main Authors COPMANS ALEX HERMAN, VERSTAPPEN WALTER LOUIS ANTOINE, VENET MARC GASTON, VANDENDRIESSCHE ANNA MARIA JOZEFA, DE KNAEP ALFONS GASTON MARIA, WILLEMSENS ALBERT LOUIS ANNA
Format Patent
LanguageEnglish
Romanian
Published 30.03.1999
Edition6
Subjects
APPARATUS THEREFOR
CHEMISTRY
GENERAL METHODS OF ORGANIC CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:PCT No. PCT/EP93/03066 Sec. 371 Date Apr. 18, 1995 Sec. 102(e) Date Apr. 18, 1995 PCT Filed Nov. 2, 1993 PCT Pub. No. WO94/11364 PCT Pub. Date May 26, 1994A process for preparing (+)-6-[(4-chlorophenyl)(1H-1,2,4-triazol-1-yl)methyl]-1-methyl-1H-benzotriazole comprising the resolution of (+/-)-6-[(4-chlorophenyl)-hydrazinomethyl)-1-methyl-1H-benzotriazole and converting the appropriate enantiomerically pure hydrazine intermediate into (+)-6-[(4-chlorophenyl)(1 H-1,2,4-triazol-1-yl)methyl]-1-methyl-1H-benzotriazole.
Bibliography:Application Number: RO19950000876