PIPERIDONAS COMO ANTAGONISTAS DE TAQUICININA

The present invention relates to a compound of the formula:- or a pharmaceutically acceptable acid addition salt or solvate thereof, wherein R is C3-C7 cycloalkyl, (C3-C7 cycloalkyl)C1-C4 alkylene or benzyl; R is phenyl optionally substituted by 1 or 2 substituents each independently selected from f...

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Bibliographic Details
Main Authors IVAN TOMMASINI, JOHN PAUL MATHIAS, DAVID NATHAN ABRAHAM FOX
Format Patent
LanguagePortuguese
Published 28.11.2003
Edition7
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to a compound of the formula:- or a pharmaceutically acceptable acid addition salt or solvate thereof, wherein R is C3-C7 cycloalkyl, (C3-C7 cycloalkyl)C1-C4 alkylene or benzyl; R is phenyl optionally substituted by 1 or 2 substituents each independently selected from fluoro and chloro; X is O or NSO2R ; and R is C1-C4 alkyl or halo(C1-C4)alkyl, together with processes for the preparation of, intermediates used in the preparation of, compositions containing and uses of, such compounds having tachykinin antagonist activity.
Bibliography:Application Number: PT19990304238T