PROCESSO PARA A PREPARACAO DE BENZODIAZEPINAS UTEIS NA PRATICA TERAPEUTICA

Benzodiazepines of formula (I) in which R9 is hydrogen or chlorine, R10 is phenyl, possibly substituted, R11 is hydrogen, R12 is oxygen or sulphur, R13 is an NH group, Ar is aromatic or heteroaromatic comprising one or more rings and in which, in particular, A is an ethylene or trimethylene bridge;...

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Main Authors ALAIN PIERRE CALVET, YVES ROBERT ALAIN PASCAL, XAVIER BERNARD LOUIS PASCAUD, FRANCOIS JOSEPH ROMAN, JEAN-LOUIS JUNIEN
Format Patent
LanguagePortuguese
Published 22.05.1991
Edition5
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Benzodiazepines of formula (I) in which R9 is hydrogen or chlorine, R10 is phenyl, possibly substituted, R11 is hydrogen, R12 is oxygen or sulphur, R13 is an NH group, Ar is aromatic or heteroaromatic comprising one or more rings and in which, in particular, A is an ethylene or trimethylene bridge; e is 1 or 2; which are gastrin antagonists and/or central antagonists of cholecystokinin.
Bibliography:Application Number: PT19900095428