PROCESSO DE PREPARACAO DE 1-ALQUIL-5-NITRO-IMIDAZOIS

Process for preparing 1-alkyl-5-nitroimidazoles of formula: (I) which comprises reacting an alkyl sulphate with an imidazole derivative of general formula: (II) in an organic solvent, and then hydrolyzing or alcoholyzing the product obtained. In the formulae (I) and (II), R denotes hydrogen, unsubst...

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Bibliographic Details
Main Authors VIVIANE MASSONNEAU, NOEL ROUY, MICHEL MULHAUSER, CLAUDE BONNAMAS
Format Patent
LanguagePortuguese
Published 08.02.1990
Edition5
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:Process for preparing 1-alkyl-5-nitroimidazoles of formula: (I) which comprises reacting an alkyl sulphate with an imidazole derivative of general formula: (II) in an organic solvent, and then hydrolyzing or alcoholyzing the product obtained. In the formulae (I) and (II), R denotes hydrogen, unsubstituted or substituted alkyl, aryl or cycloalkyl. In the formula (I), R1 denotes alkyl. In the formula (II), X denotes a group which can be removed by hydrolysis or alcoholysis.
Bibliography:Application Number: PT19890089442