PROCESSO DE PREPARACAO DE UMA COMPOSICAO FARMACEUTICA GRANULAR A BASE DE CIMETIDINA E DE COMPRIMIDOS A PARTIR DAQUELA

The present invention provides a pharmaceutical granule composition comprising cimetidine and, as a granulating agent and taste-masking agent, an ester of a polyhydroxy compound, and where desired a palatable pharmaceutically acceptable emulsifier. Particular esters are glycerol esters. The granules...

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Bibliographic Details
Main Authors EBERHARD FRITZ GOTTWALD, HERMANN PETER OSTERWALD, HORST MANFRED MACHOCZEK
Format Patent
LanguagePortuguese
Published 29.12.1989
Edition4
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention provides a pharmaceutical granule composition comprising cimetidine and, as a granulating agent and taste-masking agent, an ester of a polyhydroxy compound, and where desired a palatable pharmaceutically acceptable emulsifier. Particular esters are glycerol esters. The granules of the present invention can be used in the preparation of chewable tablets which have good palatability and bioavailability.
Bibliography:Application Number: PT19880089260