BENZOFURANIL-UREIAS SUBSTITUIDAS COM HETEROCICLOCARBONILO

Heterocyclyclarbonyl substituted benzofuranyl-ureas of formula (I) are prepared by reacting heterocyclylcarbonyl substituted 3-amino-benzofuranes with appropriate isocyanates or isothiocyanates. The unsubstituted ureas are transferred into substituted ureas by usual methods of substitution. The hete...

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Main Authors GRAHAM STURTON, MAZEN ES-SAYED, MICHAEL SPERZEL, GABRIELE BRAUNLICH, RUDIGER FISCHER, ULRICH NIELSCH, ROLF HENNING, BURKHARDT FUGMANN
Format Patent
LanguagePortuguese
Published 28.02.2002
Edition7
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Heterocyclyclarbonyl substituted benzofuranyl-ureas of formula (I) are prepared by reacting heterocyclylcarbonyl substituted 3-amino-benzofuranes with appropriate isocyanates or isothiocyanates. The unsubstituted ureas are transferred into substituted ureas by usual methods of substitution. The heterocyclylcarbonyl substituted benzofuranyl-ureas are useful as active ingredients in medicaments particularly for the treatment of acute and chronical inflammatory processes. A, D, L, R , R , R , R4 are as defined in the applications, R being a heterocyclic group.
Bibliography:Application Number: PT19960119046T