PENSO COMPREENDENDO DINITRATO DE ISOSORBETO E PREPARADO USANDO UMA MISTURA ADESIVO

The present invention provides an ISDN-containing patch that causes minimal occurrence of skin rash and has excellent percutaneous absorption and adhesive strength. The present invention discloses an isosorbide dinitrate-containing patch comprising: an adhesive layer formed on a flexible support, wh...

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Bibliographic Details
Main Authors TAKAO FUJII, MINORU FURUYA, MAKOTO IWATA, MICHISUKE OHE
Format Patent
LanguagePortuguese
Published 28.02.2002
Edition7
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The present invention provides an ISDN-containing patch that causes minimal occurrence of skin rash and has excellent percutaneous absorption and adhesive strength. The present invention discloses an isosorbide dinitrate-containing patch comprising: an adhesive layer formed on a flexible support, wherein said layer comprises an adhesive composition containing adhesive and isosorbide dinitrate, the adhesive being composed of silicone-based adhesive (A) and polyvinyl acetate-based adhesive (B), their weight ratio being A:B = 85:15 to 15:85, and the weight ratio of isosorbide dinitrate (C) to the adhesives (A+B) being (A+B):C = 90:10 to 60:40.
Bibliography:Application Number: PT19950910006T