3,4-DIAMINO-6-CHLOROPYRAZINE-2-CARBOXAMIDE COMPOUNDS FOR THE TREATMENT OF ENAC MEDIATED DISEASES

The present invention provides a compound of a formula (I): or a pharmaceutically acceptable salt thereof; a process for preparing such a compound; and to the use of such a compound in the treatment of an ENaC mediated disease state (such as asthma, CF or COPD).

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Bibliographic Details
Main Authors LENA, ELISABETH RIPA, STEPHEN CONNOLLY, GRIGORIOS NIKITIDIS, NAFIZAL HOSSAIN, ANNA KRISTOFFERSSON, SUSANNE, ELISABETH BERGLUND, MARTIN HEMMERLING, JOHAN RUNE MICHAEL LUNDKVIST, IGOR SHAMOVSKY
Format Patent
LanguageEnglish
Portuguese
Published 24.07.2018
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention provides a compound of a formula (I): or a pharmaceutically acceptable salt thereof; a process for preparing such a compound; and to the use of such a compound in the treatment of an ENaC mediated disease state (such as asthma, CF or COPD).
Bibliography:Application Number: PT20150713339T