SPLICEOSTATIN ANALOGS

The present invention is directed to novel cytotoxic spliceostatin analogs and derivatives, to antibody drug conjugates thereof, and to methods for using the same to treat medical conditions including cancer.

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Bibliographic Details
Main Authors HAIYIN HE, HUI YU YANG, MIN HE, SUJIET PUTHENVEETIL, ALESSANDRA S. EUSTAQUIO, ANOKHA SAYANI RATNAYAKE, JESSE ALEXANDER TESKE, CHRISTOPHER JOHN O'DONNELL, CHAKRAPANI SUBRAMANYAM, KENNETH JOHN DIRICO, FRANK ERICH KOEHN, MICHAEL ERIC GREEN
Format Patent
LanguageEnglish
Portuguese
Published 09.02.2018
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The present invention is directed to novel cytotoxic spliceostatin analogs and derivatives, to antibody drug conjugates thereof, and to methods for using the same to treat medical conditions including cancer.
Bibliography:Application Number: PT20130821520T