TRPV4 ANTAGONISTS

A combination comprising a compound of Formula (I): or a pharmaceutically acceptable salt thereof; and one or more other therapeutic agents, selected from the group consisting of endothelin receptor antagonists, angiotensin converting enzyme (ACE) inhibitors, angiotension II receptor antagonists, va...

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Main Authors MUI CHEUNG, TRAM H. HOANG, MARK A. HILFIKER, GUOSEN YE, HILARY SCHENCK EIDAM, JACLYN R. PATTERSON, PATRICK STOY, MARLYS HAMMOND, CARL BROOKS, KRISTA B. GOODMAN
Format Patent
LanguageEnglish
Portuguese
Published 06.06.2016
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:A combination comprising a compound of Formula (I): or a pharmaceutically acceptable salt thereof; and one or more other therapeutic agents, selected from the group consisting of endothelin receptor antagonists, angiotensin converting enzyme (ACE) inhibitors, angiotension II receptor antagonists, vasopeptidase inhibitors, vasopressin receptor modulators, diuretics, digoxin, beta blocker, aldosterone antagonists, iontropes, NSAIDS, nitric oxide donors, calcium channel modulators, muscarinic antagonists, steroidal anti-inflammatory drugs, bronchodilators, anti-histamines, leukotriene antagonist, HMG-CoA reductase inhibitors, dual non-selective ²-adrenoceptor and ± 1 -adrenoceptor antagonists, type-5 phosphodiesterase inhibitors, and renin inhibitors.
Bibliography:Application Number: PT20120814591T