APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES

Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-2 proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic Bcl-2 protein.

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Bibliographic Details
Main Authors WILLIAM J. MCCLELLAN, ANDREW M. PETROS, MICHAEL D. WENDT, CHANG H. PARK, ANDREW J. SOUERS, TODD M. HANSEN, STEVEN W. ELMORE, YUJIA DAI, LAURA HEXAMER, GEORGE A. DOHERTY, GARY T. WANG, ZHI-FU TAO, LE WANG, ROBERT A. MANTEI, XILU WANG, HONG DING, LISA HASVOLD, CHEOL-MIN PARK, AARON KUNZER, GERARD M. SULLIVAN, XIAOHONG SONG, MILAN BRUNCKO
Format Patent
LanguageEnglish
Portuguese
Published 24.09.2014
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-2 proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic Bcl-2 protein.
Bibliography:Application Number: PT20100722500T