SPIROPIPERIDINE COMPOUNDS AS ORAL-1 RECEPTOR ANTAGAGONISTEN

An ORL-1 receptor antagonist of the formula: its uses, and methods for its preparation are described. ORL-1 antagonists are deemed to be useful in the treatment of depression and/or the treatment of overweight, obesity, and/or weight maintenance post treatment for overweight or obesity. Certain comp...

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Main Authors ALMA MARIA JIMENEZ-AGUADO, CELIA LAFUENTE BLANCO, MARIA ANGELES MARTINEZ-GRAU, NURIA DIAZ BUEZO, MIGUEL ANGEL TOLEDO ESCRIBANO, ANA BELEN BENITO COLLADO
Format Patent
LanguageEnglish
Portuguese
Published 05.12.2013
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:An ORL-1 receptor antagonist of the formula: its uses, and methods for its preparation are described. ORL-1 antagonists are deemed to be useful in the treatment of depression and/or the treatment of overweight, obesity, and/or weight maintenance post treatment for overweight or obesity. Certain compounds have also demonstrated through animal models that the compounds of the present invention are useful for the treatment of migraines.
Bibliography:Application Number: PT20100782486T