BI-ARYL META-PYRIMIDINE INHIBITORS OF KINASES

The invention provides biaryl meta-pyrimidine compounds having the general structure (A). The pyrimidine compounds of the invention are capable of inhibiting kinases, such as members of the Jak kinase family, and various other specific receptor and non-receptor kinases.

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Bibliographic Details
Main Authors VED PATHAK, CHI CHING MAK, JOEL RENICK, DANIEL LOHSE, BINQI ZENG, ANDREW MC PHERSON, JOHN HOOD, JIANGUO CAO, RICHARD M. SOLL
Format Patent
LanguageEnglish
Portuguese
Published 13.10.2016
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention provides biaryl meta-pyrimidine compounds having the general structure (A). The pyrimidine compounds of the invention are capable of inhibiting kinases, such as members of the Jak kinase family, and various other specific receptor and non-receptor kinases.
Bibliography:Application Number: PT20060836583T