(BIPHENYL) CARBOXYLIC ACIDS AND DERIVATIVES THEREOF

The present invention relates to compounds having the general formula (I) with the definitions of R 1 -R 6 given below, and/or a salt or ester thereof. Furthermore the invention relates to the use of said compounds as a medicament, preferably for the treatment of Alzheimer's disease and their u...

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Main Authors JEREMY MAJOR, MIHIRO SUNOSE, SVENJA BURCKHARDT, ADELINE LEFORMAL, CYRILLE BOUSSARD, KATHRYN SMELT, VALERIE READER, ALISON REID, FRANCIS WILSON, JESS TAYLOR, RICHARD JOHN HARRISON, REMEDIOS HERNANDEZ-PERNI, ANDREW CANSFIELD
Format Patent
LanguageEnglish
Portuguese
Published 23.06.2009
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to compounds having the general formula (I) with the definitions of R 1 -R 6 given below, and/or a salt or ester thereof. Furthermore the invention relates to the use of said compounds as a medicament, preferably for the treatment of Alzheimer's disease and their use for the modulation of ³-secretase activity.
Bibliography:Application Number: PT20050799330T