NUCLEIC ACIDS FOR THE TREATMENT OF HMGB1-RELATED PATHOLOGIES

The present invention relates to the use of synthetic double-stranded nucleic acid or nucleic acid analogue molecules with a bent shape structure for the prevention and treatment of pathologies induced directly or indirectly by the HMGB1 protein.

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Bibliographic Details
Main Authors ENRICO M. BUCCI, SILVANO FUMERO, DOMENICA MUSUMECI, MARCO E. BIANCHI, DOMENICO G. BARONE, MARGHERITA VALENTE, ROBERTO SAPIO
Format Patent
LanguageEnglish
Portuguese
Published 06.10.2008
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The present invention relates to the use of synthetic double-stranded nucleic acid or nucleic acid analogue molecules with a bent shape structure for the prevention and treatment of pathologies induced directly or indirectly by the HMGB1 protein.
Bibliography:Application Number: PT20050773148T