FSH GLYCOSYLATION MUTANT

A novel FSH mutant with increased glycosylation and longer half-lifes for use in inducing folliculogenesis in human patients is described. The FSH mutant permits the use of lower cumulative doses of FSH to achieve the same or better clinical result.

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Bibliographic Details
Main Authors XULIANG JIANG, SEAN D. MCKENNA, MARK TEPPER, ROBERT K. CAMPBELL, WILLIAM H. BRONDYK, STEPHEN J. ARKINSTALL, LOUISE M. GARONE
Format Patent
LanguageEnglish
Portuguese
Published 07.07.2011
Subjects
CHEMISTRY
DERIVATIVES THEREOF
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SUGARS
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Summary:A novel FSH mutant with increased glycosylation and longer half-lifes for use in inducing folliculogenesis in human patients is described. The FSH mutant permits the use of lower cumulative doses of FSH to achieve the same or better clinical result.
Bibliography:Application Number: PT20040783331T