MACROCYCLIC CARBOXYLIC ACID AND ACYLSULFONAMIDE COMPOUND AS INHIBITOR OF HCV REPLICATION

The present application provides compounds of the general formulas I-IX as defined herein, as well as compositions, including pharmaceutical compositions, comprising a subject compound. The present application further provides treatment methods, including methods of treating a hepatitis C virus infe...

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Bibliographic Details
Main Authors LAWRENCE M. BLATT, YUTONG JIANG, MACHENDER R. DURU, GEORGE ANDREW DOHERTY, STEVEN WADE ANDREWS, JOHN ANTHONY JOSEY, KEVIN RONALD CONDROSKI, SCOTT D. SEIWERT, APRIL LAYNE KENNEDY, STEVEN MARK WENGLOWSKY, BENJAMIN T. WOODARD, PETER JOHN STENGEL
Format Patent
LanguageEnglish
Portuguese
Published 21.02.2013
Subjects
CHEMISTRY
COMPOSITIONS BASED THEREON
DERIVATIVES OF NATURAL MACROMOLECULAR COMPOUNDS
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
ORGANIC MACROMOLECULAR COMPOUNDS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
THEIR PREPARATION OR CHEMICAL WORKING-UP
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Summary:The present application provides compounds of the general formulas I-IX as defined herein, as well as compositions, including pharmaceutical compositions, comprising a subject compound. The present application further provides treatment methods, including methods of treating a hepatitis C virus infection and methods of treating liver fibrosis, the methods generally involving administering to an individual in need thereof an effective amount of a subject compound or composition.
Bibliography:Application Number: PT20040795169T