DIBENZO C CHROMEN-6-ONE DERIVATIVES AS ANTI-CANCER AGENTS

Molecules demonstrating anti-proliferative effects against epithelial cancer cell lines and endothelial cells and methods of synthesis are disclosed. The molecules are intended for use in therapeutic preparations for the treatment of cancer through either anti-angiogenesis or other anti-cancer mecha...

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Bibliographic Details
Main Authors PETER REDDEN, JOHN WHELAN, JULIE MERCURE, NATALIE LAZAROWYCH, JONATHAN MARTIN SCHMIDT, SHUGUANG ZHU
Format Patent
LanguageEnglish
Portuguese
Published 05.09.2008
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:Molecules demonstrating anti-proliferative effects against epithelial cancer cell lines and endothelial cells and methods of synthesis are disclosed. The molecules are intended for use in therapeutic preparations for the treatment of cancer through either anti-angiogenesis or other anti-cancer mechanisms. The compounds specified are 6H-dibenzo[b,d]pyran-6-one derivatives and have been shown to be antiproliferative against human endothelial cells.
Bibliography:Application Number: PT20020701135T