PROCESSO PARA A PREPARACAO DE (7S,TRANS)-2-(2-PIRIMIDINIL)-7-(HIDROXIMETIL)OCTA-HIDRO-2H-PIRIDO{1,2-A}PIRAZINA

A process for separating the enantiomers (I), (II) of a racemic mixture of trans-2-(2-pyrimidinyl)-7-(hydroxymethyl)octahydro-2H-pyrido[1,2-a]pyr azine comprising reacting the racemic mixture with D-(-) or L-(+) tartaric acid and separating the resulting diastereomeric tartrate salts.

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Bibliographic Details
Main Author CHARLES W. MURTIASHAW
Format Patent
LanguagePortuguese
Published 30.06.1999
Edition6
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:A process for separating the enantiomers (I), (II) of a racemic mixture of trans-2-(2-pyrimidinyl)-7-(hydroxymethyl)octahydro-2H-pyrido[1,2-a]pyr azine comprising reacting the racemic mixture with D-(-) or L-(+) tartaric acid and separating the resulting diastereomeric tartrate salts.
Bibliography:Application Number: PT19920100061