5-phenylthiazole derivatives and their use as Pi3 kinase inhibitors

Compounds of formula I in free or salt form, wherein R1, R2, R3, R4 and R5 have the meanings as indicated in the specification, are useful for treating diseases mediated by phosphatidylinositol 3-kinase. Pharmaceutical compositions that contain the compounds and processes for preparing the compounds...

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Main Authors OZA MRINALINI SACHIN, WHITEHEAD LEWIS, SHUKLA LENA, BRUCE IAN, BLOOMFIELD GRAHAM CHARLES, MCCARTHY CLIVE, FINAN PETER, PRESS NICOLA ELAINE, HAYLER JUDY, LEBLANC CATHERINE, KIRMAN LOUISE
Format Patent
LanguageEnglish
Polish
Published 27.05.2013
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Compounds of formula I in free or salt form, wherein R1, R2, R3, R4 and R5 have the meanings as indicated in the specification, are useful for treating diseases mediated by phosphatidylinositol 3-kinase. Pharmaceutical compositions that contain the compounds and processes for preparing the compounds are also described.
Bibliography:Application Number: PL20030403456