NOVEL METHOD OF OBTAINING N-(1,1-DIMETHYL)-4-[[5'-ETHOXY-4-CIS[2-[4-MORPHOLIN]ETHOXY]2'-OXOSPIRO[CYCLOEXANE-1,3'-[3H]INDOL]-1'(2'H)YL]-SULPHONYL]-3-METHOXYBENZAMIDE AND ITS SALTS

The invention relates to a process for the preparation of a compound of formula (I) and the salts thereof by reacting the compound of formula (II) with the compound of formula (III), which comprises carrying out the reaction in dimethyl sulfoxide, at a temperature between 10° C. and 40° C., preferab...

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Main Authors GONCZI CSABA, SIMON KALMAN, SZOMOR TIBORNE, CSIKOS EVA, EROSNE TAKACSY TUNDE, SANTANE CSUTOR ANDREA, SAROSI PETER, HERMECZ ISTVAN, HEJA GERGELY, NAGY LAJOS, SZVOBODA GYORGYNE, MAJLATH CSILLA, HALASZ JUDIT
Format Patent
LanguageEnglish
Published 25.08.2003
Edition7
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Summary:The invention relates to a process for the preparation of a compound of formula (I) and the salts thereof by reacting the compound of formula (II) with the compound of formula (III), which comprises carrying out the reaction in dimethyl sulfoxide, at a temperature between 10° C. and 40° C., preferably at room temperature and transforming the resulting base of formula (I), if desired, into its salt by a method known per se.
Bibliography:Application Number: PL20000352465