COMPOSITIONS COMPRISING 2-((1-(2(4-FLUOROPHENYL)-2-OXOETHYL)PIPERIDIN-4-YL)METHYL)ISOINDOLIN-1-ONE FOR TREATING SCHIZOPHRENIA

The disclosure provides a novel polymorph of Compound (I):, 2-((1-(2-(4-Fluorophenyl)-2-oxoethyl)piperidin-4-yl)methyl)isoindolin-1-one monohydrochloride dihydrate, i.e., Form (A) of Compound (I)*HCl*2H2O. Pharmaceutical compositions comprising Form (A) of Compound (I)*HCl*2H2O and related methods o...

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Bibliographic Details
Main Authors LUTHRINGER, REMY, WERNER, SANDRA, OKUYAMA, MASAHIRO, NOEL, NADINE
Format Patent
LanguageEnglish
Polish
Published 30.05.2022
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The disclosure provides a novel polymorph of Compound (I):, 2-((1-(2-(4-Fluorophenyl)-2-oxoethyl)piperidin-4-yl)methyl)isoindolin-1-one monohydrochloride dihydrate, i.e., Form (A) of Compound (I)*HCl*2H2O. Pharmaceutical compositions comprising Form (A) of Compound (I)*HCl*2H2O and related methods of treatment are also disclosed.
Bibliography:Application Number: PL20150808314T