CRYSTALLINE TOSYLATE SALT OF A PI3K DELTA SELECTIVE INHIBITOR FOR USE IN PHARMACEUTICAL FORMULATIONS
The divisional application relates to a pharmaceutical composition comprising a p-toluenesulfonic acid salt (PTSA) of the selective PI3K delta inhibitor (S)-2-(1-(4-amino-3-(3-fluoro-4-isopropoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)ethyl)-6-fluoro-3-(3-fluorophenyl)-4H-chromen-4-one (TGR-1202) a...
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Main Author | |
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Format | Patent |
Language | English Polish |
Published |
02.11.2021
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Subjects | |
Online Access | Get full text |
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Summary: | The divisional application relates to a pharmaceutical composition comprising a p-toluenesulfonic acid salt (PTSA) of the selective PI3K delta inhibitor (S)-2-(1-(4-amino-3-(3-fluoro-4-isopropoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)ethyl)-6-fluoro-3-(3-fluorophenyl)-4H-chromen-4-one (TGR-1202) and a solubilizer, and to the pharmaceutical composition for use in the treatment of a PI3K kinase mediated disease or disorder such as cancer. |
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Bibliography: | Application Number: PL20150733532T |