ACTIVATION OF BIOLUMINESCENCE BY STRUCTURAL COMPLEMENTATION

Provided herein are compositions and methods for the assembly of a bioluminescent complex from two or more non-luminescent (e.g., substantially non-luminescent) peptide and/or polypeptide units. In particular, bioluminescent activity is conferred upon a non-luminescent polypeptide via structural com...

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Main Authors DIXON, ANDREW S, GOUELI, SAID, ENCELL, LANCE, UNCH, JAMES, HALL, MARY, ROBERS, MATTHEW, SCHWINN, MARIE, BINKOWSKI, BROCK F, ZEGZOUTI, HICHAM, NATH, NIDHI, KIRKLAND, THOMAS, MONDAL, SUBHANJAN, MEISENHEIMER, PONCHO, PULUKKUNAT, DILEEP K, MACHLEIDT, THOMAS, WOOD, MONIKA, WOOD, KEITH, DART, MELANIE
Format Patent
LanguageEnglish
Polish
Published 14.11.2022
Subjects
CHEMISTRY
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PHYSICS
TESTING
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Summary:Provided herein are compositions and methods for the assembly of a bioluminescent complex from two or more non-luminescent (e.g., substantially non-luminescent) peptide and/or polypeptide units. In particular, bioluminescent activity is conferred upon a non-luminescent polypeptide via structural complementation with another, complementary non-luminescent peptide.
Bibliography:Application Number: PL20140769752T