HETEROCYCLIC GSK-3 ALLOSTERIC MODULATORS

The invention relates to heterocyclic derivatives of substituted quinolines as allosteric inhibitors of the glycogen synthase kinase 3 (GSK-3) enzyme. Thus, said compounds can be used in the production of a drug for the treatment and/or prevention of diseases in which GSK-3 is involved, such as: neu...

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Main Authors MARTÍNEZ GIL ANA, GIL AYUSO-GONTÁN CARMEN, PALOMO RUIZ VALLE, REYES RODRÍGUEZ JULIO ALBERTO, PÉREZ FERNÁNDEZ DANIEL I, PEREZ MARTÍN CONCEPCIÓN
Format Patent
LanguageEnglish
Polish
Published 29.12.2017
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The invention relates to heterocyclic derivatives of substituted quinolines as allosteric inhibitors of the glycogen synthase kinase 3 (GSK-3) enzyme. Thus, said compounds can be used in the production of a drug for the treatment and/or prevention of diseases in which GSK-3 is involved, such as: neurodegenerative diseases, inflammatory diseases, cancer and diabetes, as well as to promote a plurality of regenerative processes..
Bibliography:Application Number: PL12836243T