2,3 DIHYDRO-1H-INDEN-1-YL-2,7-DIAZASPIRO[3.6]NONANE DERIVATIVES AND THEIR USE AS ANTAGONISTS OR INVERSE AGONISTS OF THE GHRELIN RECEPTOR

The present invention provides a compound of Formula (I) or a pharmaceutically salt thereof wherein R1, R2, Ra, L, Z, Z1 and Z2 are as defined herein, that act as Ghrelin antagonists or inverse agonists; pharmaceutical compositions thereof; and methods of treating diseases, disorders, or conditions...

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Main Authors LONDREGAN, ALLYN TIMOTHY, CAMERON, KIMBERLY O'KEEFE, MCCLURE, KIM FRANCIS, BHATTACHARYA, SAMIT KUMAR, SIMILA, SUVI TUULA MARJUKKA, KUNG, DANIEL WEI-SHUNG, FERNANDO, DILINIE PRASADHINI
Format Patent
LanguageEnglish
Polish
Published 29.02.2016
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Summary:The present invention provides a compound of Formula (I) or a pharmaceutically salt thereof wherein R1, R2, Ra, L, Z, Z1 and Z2 are as defined herein, that act as Ghrelin antagonists or inverse agonists; pharmaceutical compositions thereof; and methods of treating diseases, disorders, or conditions mediated by the antagonism of the Ghrelin receptor.
Bibliography:Application Number: PL20110713083T