COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS

The present invention provides compounds of Formula I or II: wherein R1, R1b, R2, R3, R4, R5, R6 and R7 are defined herein. The compounds of Formula (I) or (II) and pharmaceutical compositions thereof are useful for the treatment of B-Raf-associated diseases.

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Bibliographic Details
Main Authors JIN, JEFF (XIANMING), TELLEW, JOHN, ZHANG, QIONG, PECCHI, SABINA, LIU, ZUOSHENG, COSTALES, ABRAN Q, POON, DANIEL, HUANG, SHENLIN
Format Patent
LanguageEnglish
Polish
Published 31.03.2015
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention provides compounds of Formula I or II: wherein R1, R1b, R2, R3, R4, R5, R6 and R7 are defined herein. The compounds of Formula (I) or (II) and pharmaceutical compositions thereof are useful for the treatment of B-Raf-associated diseases.
Bibliography:Application Number: PL20100745280T