FLUORINATED DERIVATIVES OF 3-HYDROXYPYRIDIN-4-ONES

Provided are compounds of Formula I which are derivatives of 3-Hydroxypyridin-4-ones. The compounds may be used in treatment of a medical condition related to a toxic concentration of iron. The compounds may be used for preparation of a medicament for treatment of a medical condition related to a to...

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Main Authors XIN, TAO, WANG, YINGSHENG, N'ZEMBA, BLAISE, LEUNG-TOUNG, REGIS, PREMYSLOVA, MARYNA, ZHAO, YANQING, SHAH, BIRENKUMAR, TAM, TIM FAT, WODZINSKA, JOLANTA MARIA
Format Patent
LanguageEnglish
Polish
Published 27.02.2015
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Provided are compounds of Formula I which are derivatives of 3-Hydroxypyridin-4-ones. The compounds may be used in treatment of a medical condition related to a toxic concentration of iron. The compounds may be used for preparation of a medicament for treatment of a medical condition related to a toxic concentration of iron. The medical condition related to a toxic concentration of iron may be selected from the group consisting of: cancer, pulmonary disease, progressive kidney disease and Friedreich's ataxia.
Bibliography:Application Number: PL20100793481T