NOVEL THIOPHENEDIAMINE DERIVATIVE HAVING UREA STRUCTURE

• Main Authors: MOGI, HIROYUKI, WATANABE, KATSUHIKO, TAJIMA, HISASHI, YAMAZAKI, YUSUKE, YONEDA, SHINJI, FUJIKAWA, JUNKO, MISHINA, NORIKO, YAMAMOTO, MINORU
• Format: Patent
• Language: English; Polish
• Published: 30.11.2012
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The present invention relates to synthetic studies of a novel thiophenediamine derivative having a urea structure and to finding pharmaceutical actions thereof. The present invention provides a compound represented by the following general formula (1) or a salt thereof. In the formula (1), R 1 and R 2 are the same or different and represent a hydrogen atom, a lower alkyl group which may have a substituent, etc. R 3 represents a hydroxy group, a lower alkoxy group which may have a substituent, a lower cycloalkyloxy group which may have a substituent, etc. R 4 and R 5 are the same or different and represent a halogen atom, a lower alkyl group, a hydroxy group, etc. X represents a lower alkylene group which may have a substituent, etc. Y represents a single bond or a lower alkylene group which may have a substituent, etc. W 1 -W 2 represents N-CH, CH-N, etc. and l and m are the same or different and represent 0, 1, etc.