Solid pharmaceutical dosage form comprising a ritonavir and lopinavir solid dispersion

A solid pharmaceutical dosage form providing improved oral bioavailability is disclosed for inhibitors of HIV protease. In particular, the dosage form comprises a solid dispersion of at least one HIV protease inhibitor in at least one pharmaceutically acceptable water-soluble polymer and at least on...

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Main Authors BERNDL, GUNTHER, REINHOLD, ULRICH, BREITENBACH, JÖRG, ROSENBERG, JÖRG, LIEPOLD, BERND, GHOSH, SOUMOJEET, ALANI, LAMAN
Format Patent
LanguageEnglish
Polish
Published 30.04.2013
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:A solid pharmaceutical dosage form providing improved oral bioavailability is disclosed for inhibitors of HIV protease. In particular, the dosage form comprises a solid dispersion of at least one HIV protease inhibitor in at least one pharmaceutically acceptable water-soluble polymer and at least one pharmaceutically acceptable surfactant.
Bibliography:Application Number: PL20100181250T