PROCESS FOR PREPARING 5-BIPHENYL-4-AMINO-2-METHYL PENTANOIC ACID

The present invention relates to pyrrolidin-2-ones according to the formula (1), or salts thereof, wherein R1 is hydrogen or a nitrogen protecting group, methods for their preparation and their use in the preparation of NEP-inhibitors, particularly in the preparation of N-(3-carboxyl-1-oxopropyl)-(4...

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Bibliographic Details
Main Authors CISZEWSKI LECH, BÄNZIGER MARKUS, WAYKOLE LILADHAR MURLIDHAR, WIETFELD BERNHARD, HAWKER STEVEN, NAPP MATTHIAS, HOOK DAVID, RUCH THOMAS, SEDELMEIER GOTTFRIED, RISS BERNHARD
Format Patent
LanguageEnglish
Polish
Published 28.02.2017
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:The present invention relates to pyrrolidin-2-ones according to the formula (1), or salts thereof, wherein R1 is hydrogen or a nitrogen protecting group, methods for their preparation and their use in the preparation of NEP-inhibitors, particularly in the preparation of N-(3-carboxyl-1-oxopropyl)-(4S)-(p-phenylphenylmethyl)-4-amino-(2R)-methyl butanoic acid ethyl ester or salt thereof.
Bibliography:Application Number: PL20080706986T