DIASTEREOMER SALTS OF (±)-ALPHA-(DIFLUOROMETHYL)ORNITHINE-MONOHYDROCHLORIDE MONOHYDRATE AND METHOD OF SEPARATION OF (+)- ALPHA-(DIFLUOROMETHYL)ORNITHINE

(±)-alpha-(Difluoromethyl)-ornithine is separate into its isomers using (-)-O,O'-di-p-toluoyl-L-tartaric acid. (-)-alpha-(Difluoromethyl)-ornithine monohydrochloride monohydrate and in particular the (-)-isomer are inhibitors of ornithine decarboxylase and thereby have numerous pharmacological...

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Bibliographic Details
Main Author MEUL THOMAS
Format Patent
LanguageEnglish
Polish
Published 31.08.2007
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
APPARATUS THEREFOR
CHEMISTRY
GENERAL METHODS OF ORGANIC CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
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Summary:(±)-alpha-(Difluoromethyl)-ornithine is separate into its isomers using (-)-O,O'-di-p-toluoyl-L-tartaric acid. (-)-alpha-(Difluoromethyl)-ornithine monohydrochloride monohydrate and in particular the (-)-isomer are inhibitors of ornithine decarboxylase and thereby have numerous pharmacological actions.
Bibliography:Application Number: PL19990346900