CYCLOSPORIN PURIFICATION PROCESS

Object of the invention is a process for the chromatographic preparation of cyclosporin A from a crude product containing cyclosporin complex by using a column filled with silica gel and by the application of multistep chromatography with a column filled with normal phase silica gel and by a solvent...

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Bibliographic Details
Main Authors DEAK LAJOS, MISKOLCZY ISTVANNE, NAGYNE ARVAI EDIT, KERI VILMOS, MAKO GYORGYNE
Format Patent
LanguageEnglish
Polish
Published 31.05.2007
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:Object of the invention is a process for the chromatographic preparation of cyclosporin A from a crude product containing cyclosporin complex by using a column filled with silica gel and by the application of multistep chromatography with a column filled with normal phase silica gel and by a solvent mixture containing toluene as the major component.
Bibliography:Application Number: PL19980330142