NOVEL COMPOUNDS 9-N-ETHENYLIC DERIVTIVES OF 9(S)-ERYTHROMYCILAMINE

The invention relates to 9-N-ethenyl derivatives of 9(S)-erythromycylamine, new semisynthetic antibiotics of the macrolide class of the general formula (I) wherein R and R are the same or different and represent nitryl, a carboxyl group of the formula COOR , wherein R represents a C1-C4 alkyl group,...

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Bibliographic Details
Main Authors PAVLOVIC DINA, KUJUNDZIC NEDJELJKO, KOBREHEL GABRIJELA, KELNERIC ZELJKO, LAZAREVSKI GORJANA
Format Patent
LanguageEnglish
Polish
Published 29.08.2003
Edition7
Subjects
CHEMISTRY
DERIVATIVES THEREOF
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SUGARS
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Summary:The invention relates to 9-N-ethenyl derivatives of 9(S)-erythromycylamine, new semisynthetic antibiotics of the macrolide class of the general formula (I) wherein R and R are the same or different and represent nitryl, a carboxyl group of the formula COOR , wherein R represents a C1-C4 alkyl group, or a keto group of the formula COR , wherein R represents a C1-C4 alkyl group, to their pharmaceutically acceptable addition salts with inorganic or organic acids, to a process for their preparation, to a process for the preparation of the pharmaceutical compositions as well as to the use of the obtained pharmaceutical compositions in the treatment of bacterial infections.
Bibliography:Application Number: PL19970322862