DIPHENYLPROPYLAMINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF

Diphenylpropylamine derivatives of the formula I in which: R denotes hydrogen or methyl, R denotes hydrogen, methyl or n-decyl, Z (a) denotes a phenyl group substituted by R , R and R , in which: R denotes hydrogen, fluorine, chlorine or bromine, nitro, C1-12-alkyl, C1-4-alkoxy, phenoxy or benzyloxy...

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Main Authors SANDOR VIRAG, EVA UDVARI, GYUTA PAPP, LASZLO TARDOS, ZOLTAN VARGAI, GABOR KOVACS, PAL KISS, ANDREA SANTANE CSUTOR, LASZLO SKEKERES, DEZSO KORBONITS, VERA GERGELY, IMRE BATA, KATALIN MARMAROSI NEE KELLNER, PETER KORMOCZY
Format Patent
LanguageEnglish
Published 18.07.1990
Edition5
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Diphenylpropylamine derivatives of the formula I in which: R denotes hydrogen or methyl, R denotes hydrogen, methyl or n-decyl, Z (a) denotes a phenyl group substituted by R , R and R , in which: R denotes hydrogen, fluorine, chlorine or bromine, nitro, C1-12-alkyl, C1-4-alkoxy, phenoxy or benzyloxy, R and R denotes hydrogen, chlorine, hydroxyl, alkoxy, benzyloxy, acetamido or carboxyl or R and R together denote methylenedioxy or (b) denotes 4-methoxynaphthyl or 4-ethoxynaphthyl, and R denotes hydrogen or fluorine, with the proviso that R , R , R , R , R and R do not simultaneously denote hydrogen atoms, and their physiologically tolerable acid addition salts are used as active substances in pharmaceutical agents which can primarily be advantageously used for the therapy of cardiac and circulatory disorders.
Bibliography:Application Number: PH19870035508