BIDENS PILOSA ETHANOL EXTRACT ANTIHYPERTENSIVE TABLET

• Main Authors: ALTO, Philip Reginald C, TORALBA, Joanna V, HERNANDEZ, Christine C, SEDUCO, Noriel A, TUTOR, Jasmin, LARCIA II, Levi Letlet H, GONZAGA, John Lester C, FABIAN, Mavis Colleen P, SANCHEZ, Arlyn C, IBA¥EZ, Herian Marie T, FONTILLAS, Rebecca Grace L, QUINIQUITO, Rudy Leo L, CRUZ, Paul Felipe S, BULATAO, Bryan Paul I, GUARINO, Emyflor L, ENCARNACION, Patrick James C
• Format: Patent
• Language: English
• Published: 09.07.2021
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The present utility model relates to a Bidens pilosa ethanol extract antihypertensive tablet, comprising a ground, dried plant material extracted using ten (10) liters of ethanol for 24 hours making a first extraction; a marc extracted again using ten (10) liters of ethanol for another 24 hours making a second extraction; a bulk extract pooled from the first and the second extractions; the bulk extract subjected to vacuum concentration at 60-70øC to produce a concentrate; the concentrate filtered and homogenized using 20-40 pcnt of a homogenizing solution to form a homogenized solution; the homogenized solution spray-dried at 170-180øC inlet and 70-80øC outlet to make the Bidens pilosa ethanol extract; said Bidens pilosa ethanol extract mixed with an equivalent weight of colloidal silicon dioxide and an appropriate amount of starch making a first mixture; another set of starch sieved and mixed with sufficient water until the formation of paste making a second mixture; said first and second mixtures mixed via geometric dilution to form a wet mass; the wet mass screened through mesh #4, then dried at 60øC until a proper sampling of the meshed mass has a moisture content of not greater than 3 pcnt ; meshed mass screened through sieves #20 and #40, and labeled as good granules and fine granules, respectively; and said good and fine granules proportionately mixed with magnesium stearate.