OMEGA-CYCLOALKYL PROSTAGLANDINS

This invention encompasses prostaglandins of the formula Iwherein X represents cis or trans -CH=CH-, -C≡-, methylene or ethylene;R, represents a cycloalkyl group of the formulawhere m is 1 to 3 inclusiveR2 represents hydrogen or lower alkyl with the proviso that the sum of the carbon atoms in X and...

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Bibliographic Details
Main Authors COLLINS PAUL WADDELL, GASIECKI ALAN FRANK
Format Patent
LanguageEnglish
Published 11.12.1987
Edition3
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:This invention encompasses prostaglandins of the formula Iwherein X represents cis or trans -CH=CH-, -C≡-, methylene or ethylene;R, represents a cycloalkyl group of the formulawhere m is 1 to 3 inclusiveR2 represents hydrogen or lower alkyl with the proviso that the sum of the carbon atoms in X and R, is 7 or less.R' represents lower alkyl containing 1 to 6 carbon atoms, vinyl or ethynyl;wherein R''' represents hydroxymethyl, hydroxyacetyl or -CO2 R'''wherein R"" represents hydrogen or lower alkyl containing 1 to 6 carbon atoms and the wavy line represents optional R or S stereochemistry.
Bibliography:Application Number: PH19840031444