BENZOLACTAM COMPOUNDS AS PROTEIN KINASE INHIBITORS
The invention provides a compound of formula (0): or a pharmaceutically acceptable salt, N-oxide or tautomer thereof. The compounds are inhibitors of ERK 1/2 kinases and will be useful in the treatment of ERKl/2-mediated conditions. The compounds are therefore useful in therapy, in particular in the...
Saved in:
Main Authors | , , , , , , , , , , , , , , |
---|---|
Format | Patent |
Language | English |
Published |
01.10.2018
|
Subjects | |
Online Access | Get full text |
Cover
Loading…
Abstract | The invention provides a compound of formula (0): or a pharmaceutically acceptable salt, N-oxide or tautomer thereof. The compounds are inhibitors of ERK 1/2 kinases and will be useful in the treatment of ERKl/2-mediated conditions. The compounds are therefore useful in therapy, in particular in the treatment of cancer. |
---|---|
AbstractList | The invention provides a compound of formula (0): or a pharmaceutically acceptable salt, N-oxide or tautomer thereof. The compounds are inhibitors of ERK 1/2 kinases and will be useful in the treatment of ERKl/2-mediated conditions. The compounds are therefore useful in therapy, in particular in the treatment of cancer. |
Author | HEIGHTMAN, Thomas Daniel O'REILLY, Marc COOKE, Michael Liam BUCK, Ildiko Maria COUSIN, David DAY, James Edward Harvey ONIONS, Stuart Thomas HOWARD, Steven WOOLFORD, Alison Jo-Anne WATTS, John Paul NORTON, David BERDINI, Valerio GRIFFITHS-JONES, Charlotte Mary SHANNON, Jonathan Martin MURRAY, Christopher William |
Author_xml | – fullname: DAY, James Edward Harvey – fullname: ONIONS, Stuart Thomas – fullname: GRIFFITHS-JONES, Charlotte Mary – fullname: COUSIN, David – fullname: MURRAY, Christopher William – fullname: WOOLFORD, Alison Jo-Anne – fullname: SHANNON, Jonathan Martin – fullname: BUCK, Ildiko Maria – fullname: HEIGHTMAN, Thomas Daniel – fullname: NORTON, David – fullname: BERDINI, Valerio – fullname: O'REILLY, Marc – fullname: HOWARD, Steven – fullname: COOKE, Michael Liam – fullname: WATTS, John Paul |
BookMark | eNrjYmDJy89L5WQwcnL1i_L3cXQOcfRVcPb3DfAP9XMJVnAMVggI8g9x9fRT8Pb0cwx2VfD08_B08gzxDwrmYWBNS8wpTuWF0twMKm6uIc4euqkF-fGpxQWJyal5qSXxAR6GRgaGFqYGBuaWRo6GxkQqAwB-aSoG |
ContentType | Patent |
DBID | EVB |
DatabaseName | esp@cenet |
DatabaseTitleList | |
Database_xml | – sequence: 1 dbid: EVB name: esp@cenet url: http://worldwide.espacenet.com/singleLineSearch?locale=en_EP sourceTypes: Open Access Repository |
DeliveryMethod | fulltext_linktorsrc |
Discipline | Medicine Chemistry Sciences |
ExternalDocumentID | PH12018500792A1 |
GroupedDBID | EVB |
ID | FETCH-epo_espacenet_PH12018500792A13 |
IEDL.DBID | EVB |
IngestDate | Fri Oct 04 05:02:37 EDT 2024 |
IsOpenAccess | true |
IsPeerReviewed | false |
IsScholarly | false |
Language | English |
LinkModel | DirectLink |
MergedId | FETCHMERGED-epo_espacenet_PH12018500792A13 |
Notes | Application Number: PH20181500792 |
OpenAccessLink | https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20181001&DB=EPODOC&CC=PH&NR=12018500792A1 |
ParticipantIDs | epo_espacenet_PH12018500792A1 |
PublicationCentury | 2000 |
PublicationDate | 20181001 |
PublicationDateYYYYMMDD | 2018-10-01 |
PublicationDate_xml | – month: 10 year: 2018 text: 20181001 day: 01 |
PublicationDecade | 2010 |
PublicationYear | 2018 |
RelatedCompanies | OTSUKA PHARMACEUTICAL CO., LTD |
RelatedCompanies_xml | – name: OTSUKA PHARMACEUTICAL CO., LTD |
Score | 3.1733859 |
Snippet | The invention provides a compound of formula (0): or a pharmaceutically acceptable salt, N-oxide or tautomer thereof. The compounds are inhibitors of ERK 1/2... |
SourceID | epo |
SourceType | Open Access Repository |
SubjectTerms | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
Title | BENZOLACTAM COMPOUNDS AS PROTEIN KINASE INHIBITORS |
URI | https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20181001&DB=EPODOC&locale=&CC=PH&NR=12018500792A1 |
hasFullText | 1 |
inHoldings | 1 |
isFullTextHit | |
isPrint | |
link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwhV1LT4NAEJ401ag3rRpfNRwabsSwsE05EAMLDRhhCVDTeGm6PJIepI3F-PcdkPq46G13J5l9JDPfzOzsLMBIJUVBSqoqlOYTRReaoYhlRhVi6JqmC7T4yyagH4Rjb6Y_zOm8By-7tzBtndD3tjgiSlSG8l63-nrzHcRy2tzK7Z1Y4dD6fpqajtx5xwhXqHZlxzbdiDucyYyZkSeHsak2RIqAaBALnaW9xpJuSu27T3bzMGXzE1Wmx7AfIcOqPoFeUQ3gkO0-XxvAQdDdeWOzE7_tKRDbDZ_5o8VSK5AYDyI-C51EshIpinnq-qGEzriVuJIfer7tpzxOzmA0dVPmKTj54muzi8j7tVTtHPrVuiouQCL5JFMzNH9EmSPsZsbY0ATJl3QpRJYb-iUM_2R19Q_9Go6a7mem2g3069e3YoiIW4vb9pw-AO_9fl0 |
link.rule.ids | 230,309,786,891,25594,76904 |
linkProvider | European Patent Office |
linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwhV1LT4NAEJ401VhvWjW-qhwabsSwsLUciIGFBrQspFDTeGm6PBIP0sZi_PsO2Pq46G2zk8w-kplvZnZmFqCvkjwnBVUVSrOhogvNUMQipQoxdE3TBVr8RR3QD_jAm-r3Mzprwcu2FqbpE_reNEdEiUpR3qtGX6--g1hOk1u5vhHPOLW8GyWmI2-8Y4QrVLuyY5tuFDohkxkzI0_mE1OtiRQB0SAWOks7t-gV1q323Ue7LkxZ_USV0QHsRsiwrA6hlZdd6LDt52td2As2b9443Ijf-giI7fKncGyxxAokFgZROOVOLFmxFE3CxPW5hM64FbuSzz3f9pNwEh9Df-QmzFNw8fnXYeeR92ur2gm0y2WZn4JEsmGqpmj-iCJD2E2NgaEJki3oQog0M_Qz6P3J6vwf-jV0vCQYz8c-f7iA_Zr0mbV2Ce3q9S3vIfpW4qq5sw_-7oFI |
openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Apatent&rft.title=BENZOLACTAM+COMPOUNDS+AS+PROTEIN+KINASE+INHIBITORS&rft.inventor=DAY%2C+James+Edward+Harvey&rft.inventor=ONIONS%2C+Stuart+Thomas&rft.inventor=GRIFFITHS-JONES%2C+Charlotte+Mary&rft.inventor=COUSIN%2C+David&rft.inventor=MURRAY%2C+Christopher+William&rft.inventor=WOOLFORD%2C+Alison+Jo-Anne&rft.inventor=SHANNON%2C+Jonathan+Martin&rft.inventor=BUCK%2C+Ildiko+Maria&rft.inventor=HEIGHTMAN%2C+Thomas+Daniel&rft.inventor=NORTON%2C+David&rft.inventor=BERDINI%2C+Valerio&rft.inventor=O%27REILLY%2C+Marc&rft.inventor=HOWARD%2C+Steven&rft.inventor=COOKE%2C+Michael+Liam&rft.inventor=WATTS%2C+John+Paul&rft.date=2018-10-01&rft.externalDBID=A1&rft.externalDocID=PH12018500792A1 |