THIENO [2,3-C] PYRROL-4-ONE DERIVATIVES AS ERK INHIBITORS

The present invention provides thieno[2,3-c]pyrrol-4-one compounds that inhibit activity of extracellular-signal-regulated kinase (ERK) and may be useful in the treatment of cancer.

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Bibliographic Details
Main Authors MCMILLEN, William T, CORTEZ, Guillermo S, JOSEPH, Sajan, MCLEAN, Johnathan Alexander, RODRIGUEZ, Michael John, ZHAO, Gaiying
Format Patent
LanguageEnglish
Published 27.11.2017
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention provides thieno[2,3-c]pyrrol-4-one compounds that inhibit activity of extracellular-signal-regulated kinase (ERK) and may be useful in the treatment of cancer.
Bibliography:Application Number: PH20171501155