POLYENE MACROLIDE DERIVATIVE

Provided is an amphotericin B derivative represented by formula (I). [In formula (I), each symbol is as defined in the description.] The aforesaid compound, which is characterized by having a urea structure, cyclic structure, hydroxyalkyl or substituted monoalkylcarbamoyl at the 16-position (X), has...

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Bibliographic Details
Main Authors MIYAZAKI, Keisuke, OHARA, Takafumi, OGATA, Yuki, FUJITANI, Manabu, SUZUKI, Naoyuki, TAKAYA, Kenji, SUGIMOTO, Hideki
Format Patent
LanguageEnglish
Published 13.02.2017
Subjects
CHEMISTRY
DERIVATIVES THEREOF
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SUGARS
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Summary:Provided is an amphotericin B derivative represented by formula (I). [In formula (I), each symbol is as defined in the description.] The aforesaid compound, which is characterized by having a urea structure, cyclic structure, hydroxyalkyl or substituted monoalkylcarbamoyl at the 16-position (X), has an antifungal activity.
Bibliography:Application Number: PH20161502357