PROCESS FOR MANUFACTURING A PHARMACEUTICAL DOSAGE FORM COMPRISING NIFEDIPINE AND CANDESARTAN CILEXETIL

• Main Authors: KNOP, KLAUS, JUST, SARAH, MEENERS, ANDREAS, MEYER, G�NTER, FUNKE, ADRIAN, SMIKALLA, MARTINA, WIRGES, MARKUS, ZEITLER, JOCHEN, AXEL, KLEINEBUDDE, PETER, BROCK, DANIELA, BOEGGERING, ROLF-ANTON
• Format: Patent
• Language: English
• Published: 22.12.2014
• Subjects: BABY COMFORTERS; CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICALPURPOSES; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; DEVICES FOR RECEIVING SPITTLE; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGINGPHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL ORADMINISTERING FORMS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES

The present invention relates to manufacturing processes for the preparation of a pharmaceutical dosage form comprising nifedipine and candesartan cilexetil and optionally at least one diuretic characterized in that nifedipine is released in the body in a controlled (modified) manner and the candesartan cilexetil is released rapidly (immediate release (IR)) and optionally the diuretic is released rapidly (immediate release (IR)) and the pharmaceutical dosage forms obtainable by these processes.