ANALOGOS DE AMILINA
SE REFIERE A ANALOGOS DE AMILINA DE FORMULA R1-Z-R2, EN DONDE R1 ES H, ACILO C1-4, BENZOILO, ENTRE OTROS; R2 ES OH O NHR3, DONDE R3 ES H O ALQUILO C1-3; Z ES UNA SECUENCIA DE AMINOACIDOS SELECCIONADA DE: RCNTATCATQRLADFLHRSSF-Gly(Me)-A-Ile(Me)-LSSTEVGSETP; RCNTATCATQRLADFLHRSSNNF-Gly(Me)-A-lle(Me)-L...
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Main Authors | , , , , , , , , |
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Format | Patent |
Language | Spanish |
Published |
09.03.2018
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Subjects | |
Online Access | Get full text |
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Summary: | SE REFIERE A ANALOGOS DE AMILINA DE FORMULA R1-Z-R2, EN DONDE R1 ES H, ACILO C1-4, BENZOILO, ENTRE OTROS; R2 ES OH O NHR3, DONDE R3 ES H O ALQUILO C1-3; Z ES UNA SECUENCIA DE AMINOACIDOS SELECCIONADA DE: RCNTATCATQRLADFLHRSSF-Gly(Me)-A-Ile(Me)-LSSTEVGSETP; RCNTATCATQRLADFLHRSSNNF-Gly(Me)-A-lle(Me)-LSSTNVGSNT-Apr; y RCNTATCATQRLAHFLHRSSNNF-Gly(Me)-A-lle(Me)-LSSTNVGSNT-Apr. TAMBIEN SE REFIERE A UNA COMPOSICION FARMACEUTICA UTIL EN EL TRATAMIENTO DE OBESIDAD, DIABETES
The present invention relates to amylin analogues and to their use in the treatment or prevention of a variety of diseases, conditions or disorders, including obesity, excess food intake and associated metabolic diseases such as diabetes. The analogues have good physical and chemical stability, good solubility, and a long duration of action, and are well suited for use in the form of a liquid formulation. |
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Bibliography: | Application Number: PE2017001497 |