COMPUESTOS DE PPAR

• Main Authors: DAVID AUSTEN PERRY, CHERYL MYERS HAYWARD
• Format: Patent
• Language: Spanish
• Published: 30.09.2002
• Edition: 7
• Subjects: ACYCLIC OR CARBOCYCLIC COMPOUNDS; ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM; CHEMISTRY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

ACTIVADORES DE PPAR ALFA, COMPOSICIONES FARMACEUTICAS QUE CONTIENEN TALES COMPUESTOS Y EL USO DE TALES COMPUESTOS PARA ELEVAR CIERTOS NIVELES DE LIPIDOS EN PLASMA, INCLUYENDO EL COLESTEROL ASOCIADO A LIPOPROTEINAS DE ALTA DENSIDAD, Y PARA REDUCIR OTROS NIVELES DE LIPIDOS EN PLASMA, TALES COMO EL COLESTEROL ASOCIADO A LDL Y LOS TRIGLICERIDOS Y, POR CONSIGUIENTE, PARA TRATAR ENFERMEDADES QUE ESTAN EXACERBADAS POR BAJOS NIVELES DE COLESTEROL HDL Y/O ALTOS NIVELES DE COLESTEROL LDL Y TRIGLICERIDOS, TALES COMO LA ATEROSCLEROSIS Y ENFERMEDADES CARDIOVASCULARES EN MAMIFEROS, INCLUYENDO LOS SERES HUMANOS. PPAR alpha activators, pharmaceutical compositions containing such compounds and the use of such compounds to elevate certain plasma lipid levels, including high density lipoprotein-cholesterol and to lower certain other plasma lipid levels, such as LDL-cholesterol and triglycerides and accordingly to treat diseases which are exacerbated by low levels of HDL cholesterol and/or high levels of LDL-cholesterol and triglycerides, such as atherosclerosis and cardiovascular diseases, in mammals, including humans.