Ketolide antibiotics

This invention relates to compounds of the formula 1:and to pharmaceutically acceptable salts and solvates thereof wherein X , X , R , R , R , R and R are as defined herein. The compounds of formula 1 are antibacterial and antiprotozoal agents that may be used to treat various bacterial and protozoa...

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Bibliographic Details
Main Authors TAKUSHI KANEKO, WILLIAM THOMAS MCMILLEN
Format Patent
LanguageEnglish
Published 19.07.2005
Edition7
Subjects
CHEMISTRY
DERIVATIVES THEREOF
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SUGARS
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Summary:This invention relates to compounds of the formula 1:and to pharmaceutically acceptable salts and solvates thereof wherein X , X , R , R , R , R and R are as defined herein. The compounds of formula 1 are antibacterial and antiprotozoal agents that may be used to treat various bacterial and protozoal infections and disorders related to such infections. The invention also relates to pharmaceutical compositions containing the compounds of formula 1 and to methods of treating bacterial and protozoal infections by administering the compounds of formula 1.
Bibliography:Application Number: OA20011000191