Compounds, compositions and methods for modulating eukaryotic initiation factor 2b

The present disclosure relates generally to eukaryotic initiation factor 2B modulators, or a pharmaceutically acceptable salt, stereoisomer, mixture of stereoisomers or prodrug thereof, and methods of making and using thereof. Compounds are useful in treating diseases such as Alzheimer's, Parki...

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Main Authors Fox, Brian, Hale, Christopher R. H, Lexa, Katrina W, Craig, Robert A, Osipov, Maksim, De Vicente Fidalgo, Javier, Feng, Jianwen A, Remarchuk, Travis, Sweeney, Zachary K, Estrada, Anthony A
Format Patent
LanguageEnglish
Published 23.02.2024
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
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Summary:The present disclosure relates generally to eukaryotic initiation factor 2B modulators, or a pharmaceutically acceptable salt, stereoisomer, mixture of stereoisomers or prodrug thereof, and methods of making and using thereof. Compounds are useful in treating diseases such as Alzheimer's, Parkinson's, ALS and frontotemporal dementia.
Bibliography:Application Number: NZ20180760919